Study of the Passive Properties of the Axon

Many squids have giant axons that result from the fusion of a number of small axons. The giant axon runs along the dorsal side of the mantle of the squid. The axon may be separated from the stellate ganglion and dissected out of the squid . The giant axon may cleaned from other nerve fibers and laid down on a recording chamber. To study the cable properties of the axon, all the voltage dependent conductances are blocked. Acurrent generator is used to inject current into the axon with an internal electrode impaled through the membrane with respect to an external electrode located far away from the injection point. Most of the current will tend to exit the axon near the internal electrode and less towards the distal regions. The distribution of the currents is shown in the current plot. and the voltage distribution as a function of distance and time is shown in the Voltage Plot